The two reactants imine and enamine line up for the mannich reaction with si facial attack of the imine by the si face of the enamine aldehyde relief of steric strain dictates that the alkyl residue r of the enamine and the imine group are antiperiplanar on hellip.

This set of pages originates from professor hans reich uw madison advanced organic chemistry course chem 547 it describes electron pushing arrows the movement of a pair of electrons from an electron rich site a lone pair of electrons or a bond to an electron poor site a set of common electron pushing mechanisms are also provided here.